Breast Cancer
#1 Breast cancer A study from the National Institute on Aging
in Baltimore looked at mice who were given resveratrol and then implanted with
breast cancer cells. When compared with
the mice not given resveratrol, the study group had a dramatic decrease in the
amount of spread of cancer cells to the lungs.
This was done at low doses and could benefit breast cancer patients.
J Immunol 2013 Oct 15: 4141-4151
#2 Breast cancer This study from Mexico City looked at breast
cancer cells in cell cultures. These
cells were exposed to doxorubicin which is one of the more effective
chemotherapy agents against breast cancer.
Half of the cells were previously exposed to resveratrol. The presence of resveratrol prior to exposure
to doxorubicin enhanced the ability of the drug to kill the cancer cells. Further studies are looking at using
resveratrol clinically prior to or with exposure to doxorubicin in breast
cancer patients. PLoS 2013 May 27
#3 Breast cancer Another
study on breast cancer comes from Saudi Arabia and is also looking at
doxorubicin in the treatment of breast cancer.
This also was a study using cancer cells in cell cultures. Despite the fact that this is a good drug for
breast cancer, one of the major side effects is damage to the heart
muscle. This can limit the use of the
drug. This study was looking at
combining resveratrol which increases the ability to kill cancer cells with
lower doses of the doxorubicin. This in
turn would lower the potential damage to heart muscle cells without
compromising the effect on the cancer cells, making the drug safer and at least
as effective.
Cancer Cell Int 2012 Nov 16
#4 Breast
cancer A study from the University
of Oklahoma is looking at the use of resveratrol in combination with radiation
therapy for breast cancer. Radiation
along with chemotherapy and surgery are the three cornerstones of treatment for
breast cancer. The use of radiation can
be limited because of side effects from the amount of radiation needed to cause
cell deaths. In the study, cancer cells in cell cultures were divided in
half and half were given resveratrol in advance. All of the cells were then exposed to
radiation. The resveratrol resulted in
sensitizing the cancer cells to radiation resulting in a much more effective
induction of cell death in those cells pretreated with resveratrol, making
radiation more effective and safer.
Radiat Oncol 2013, Mar 4
