HEART DISEASE, DIABETES, COLORECTAL CANCER, ADHESIONS

Heart Disease, Diabetes, Colorectal Cancer, Adhesions

I salute your interest in Resveratrol and clinical studies associated with it.  If you are fairly new to this site, I would suggest scrolling down to the very first posting which is at the very bottom or end of this blog.  It gives background to this site.  For the record, there are now 4919 scientific articles on Resveratrol published in medical journals in the National Library of Medicine.  That is where the following articles come from, www.pubmed.com.

HEART DISEASE  From the Russian Academy of Medical Science in Moscow comes a review article on dietary polyphenols, of which Resveratrol is a part.  They showed that several studies link a decrease in cardiovascular disease (CVD) mortality rate with certain diets.  Diets rich in vegetables, fruits, unrefined cereals, legumes, nuts, garlic, olive oil and red wine.  Mediterranean diets incorporate the above and are associated with lower CVD mortalities. Resveratrol is a part of this cardioprotective action.

Bratisl Lek Listy 2012: 476-80

DIABETES  A study from a pharmacy college in India was published using human subjects with Type II diabetes on oral medications.  Half of the 62 patients were given their usual oral medications and the other half received 250 mg per day along with their regular medications for three months.  The Resveratrol group had a significant improvement in Hemoglobin A1c (a measure of blood sugar control), decreased blood pressure, and decreased total cholesterol.  There was no change in body weight or HDL (the good cholesterol).  The conclusion was that “Resveratrol is thus found to be effective in improving glycemic control” and may “provide  a potential adjuvant for the treatment and management of diabetes”.

Nutr Res 2012 July 537-41

COLORECTAL CANCER Another human study. A researcher from St James University Hospital in West Yorkshire, UK published his study of patients with Familial Adenomatous Polyposis  (FAP).  This a group of people who have inherited a gene which causes multiple polyps in the colon which in turn increases the risk of getting full-blown colorectal cancer.  Half of a group of these people were given supplemental Resveratrol and the other not.  The group treated with with the nutriceutical product had fewer and smaller polyps on colonoscopy than the untreated group.  Phase III trials are starting on this subject.

Recent Results Cancer Res 2012: 143-56

COLORECTAL CANCER  Colon cancer ranks third in cancer related mortalities, and certain phytochemicals including Resveratrol are being studied to prevent the onset of colon cancer.  A group from Meharry Medical Medical College in Nashville, TN took a group of mice and fed half with a chemical (benzo-a-pyrene) which causes colon cancer, for 60 days.  The other half was fed the chemical along with Resveratrol for 60 days.  The mice were then killed and the number of tumors in each animal was counted.  The Resveratrol group had fewer tumors.  They also had fewer areas of pre-cancer changes and under the microscope Resveratrol sped up cancer cell deaths  and decreased cell growth

J Nutr Biochem 2012 Aug.

ADHESIONS  At the Ankara Education and Research Hospital in Turkey, post-operative adhesions were studied.  This formation of troublesome scar tissue is a common problem after pelvic surgery.  A group of of rats was divided into thirds.  One third got Resveratrol 10 days before and 20 days after surgery.  The second third received Resveratrol orally for 20 days after surgery and the remainder received nothing.  They all were operated on in the pelvic area.  The rats were then killed 3 weeks later and studied for the number of adhesions and the severity of the adhesions.  Both Resveratrol groups did much better than the non- Resveratrol group.  The first group did much better with Resveratrol given before and after surgery than the second group.  Giving Resveratrol before and after pelvic surgery is an effective way to prevent or minimize adhesions after pelvic surgery in rats.

Hum Fertil 2012 Aug 9

Hopefully something in these articles was of interest.  We are starting to see more human studies and Resveratrol research is looking at a wider variety of places where it can be beneficial.  As always, I still believe Shaklee’s Vivix to be the most potent, purest,and most effective source of Resveratrol.

Until next time,

Dr Bob