Monday, February 16, 2015

ALZHEIMERS

Welcome again to our blog.  Since the last one was written 200 particles in medical journals have been published on resveratrol.  This month we will focus on Alzheimer's disease

Alzheimer's--from the School of Medicine in Qingdao University, China comes a report looking at resveratrol as a therapeutic alternative to existing treatments for Alzheimer's.  One of the mechanisms of Alzheimer's disease is protein being deposited in brain tissue in an abnormal fashion.  This group summarizes the many studies that have been done showing the neuro protective effects of resveratrol and specifically focusing on the protein deposition.  It does prevent that process and in turn prevents progression of typical Alzheimer's brains in experimental animals.  PMID 25525597

Alzheimer's--from the Mount Sinai school of medicine in New York comes another article reviewing the benefits of resveratrol.  They state that 1 in 10 Americans have Alzheimer's changes over the age of 65 and almost half of all Americans have them over the age of 85.  While there are many heart attack or cancer survivors, there are no Alzheimer's disease survivors.  The point to the growing evidence of resveratrol  shows that it has a beneficial influence in slowing  down the progression of Alzheimer's disease.  In addition to Alzheimer's,  it also has a neuro protective effect against other disorders such as multiple sclerosis, Parkinson's disease and ALS or Lou Gehrig's disease.  Studies within the last few years are showing a growing evidence of a positive impact that resveratrol is having on the treatment of Alzheimer's.  PMID 25315300

Alzheimer's--this paper was written at McGill University in Montréal.  It showed that in low to moderate red wine consumption (a source of resveratrol) there appeared to be a reduction in age related neurologic disorders including macular degeneration, stroke, and learning deficits and memory deficits with or without dementia.  It increases the clearance of the abnormal proteins that are deposited as a key feature of Alzheimer's.  This also is a review article on clinical studies and is a part of a larger study on resveratrol.  PMID25281824


Alzheimer's--this is a paper written from the University of Barcelona in Spain on familial Alzheimer's disease using a mouse model.  It was looking at the deposition of the abnormal protein in the brain tissue of Alzheimer's mice which is called amyloid beta protein.  Long-term use of resveratrol significantly prevented memory loss and decreases  the amount of amyloid deposited in the brain tissue, thus providing a protective effect against Alzheimer's symptoms progression, and improving memory.  PMID 25024312

Dr. Bob

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