Monday, February 16, 2015

OBESITY, OSTEOPOROSIS, ENDOMETRIOSIS


Thank you for joining us once again.  This month we are covering a variety of conditions, which can be helped by the use of resveratrol.

Obesity--from the University of Valladolid in Spain comes a steady of the use of resveratrol in obese mice.  15 mice were placed on a long-term hyper-caloric diet and resveratrol and were monitored for weight, survival, blood sugar, insulin, cholesterol and triglycerides.  They also measured neuromuscular coordination.  The mice were fed since they were 3 months old.  When compared to a group of mice on high calorie diet without resveratrol, the treated mice had a 5-7% reduction in weight fairly quickly and over one year also had lower levels of blood sugar, insulin and cholesterol along with improved neuromuscular coordination.  While not a human study, this is encouraging to the overweight portion of our population.  PMID 25386805

Post menopausal osteoporosis--this study comes from the Military Medical University in Xian, China.  Post menopausal osteoporosis is a common issue and there is constant effort to find treatments with minimal side effects.  This particular study was done using a rat model where the ovaries were removed inducing menopause.  They were then divided into 4 groups, 3 of which were given a higher dose of resveratrol than the group before.  the fourth group was a control group with ovaries removed but not given resveratrol.  The higher the dose the more benefit seen and a decreased loss of bone mineral density.  Bone structure was improved when compared to the rats who were not given resveratrol.  This suggested a therapeutic benefit against osteoporosis with no side effects.  PMID 25377437

Endometriosis--from Yeditepe University Hospital in Istanbul, Turkey came a study on using resveratrol to treat endometrial implants.  Again, rats were used and endometriosis was induced experimentally by surgically implanting endometrial tissue into the abdomens of the rats.  The rats were then divided into those treated with resveratrol and those which were not.  After treatment, the rats underwent another surgery for exploration and evaluation of the implants in the 2 groups.  The resveratrol group appeared to have an inhibiting factor in the growth  and inflammation of the endometrial implants.  Again this is not a human study but does offer hope to those were suffering from this condition, again with a product which has no side effects.  PMID 25373440 

I hope you find these medical papers of interest and look forward to human studies for the same conditions.
To Your Health,
Dr. Bob

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